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ea0073aep7 | Adrenal and Cardiovascular Endocrinology | ECE2021

Unnecessary cosyntropin stimulation tests for nonclassic congenital adrenal hyperplasia (NCAH) – shall the cut-off value of 17-hydroxyprogesterone be revised?

Bartosz Domagala , Trofimiuk-Muldner Malgorzata , Krawczyk Anna , Joanna Topór-Kolkowska , Skalniak Anna , Przybylik-Mazurek Elwira , Pach Dorota , Hubalewska-Dydejczyk Alicja

Cosyntropin stimulation test is the gold diagnostic standard used to test for NCAH. Genetic testing is not currently considered to be the primary diagnostic tool for NCAH. Still, it may be helpful in establishing a diagnosis if other results are unequivocal or for genetic counselling purposes. The study aimed at verifying the currently accepted threshold of 17-hydroxyprogesterone (17OHP) level (3 2.0 ng/ml) at which a cosyntropin stimulation test should be performed...

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Unnecessary cosyntropin stimulation tests for nonclassic congenital adrenal hyperplasia (NCAH) – shall the cut-off value of 17-hydroxyprogesterone be revised?

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